The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Jun. 04, 2018
Applicant:
Janssen Pharmaceutica NV, Beerse, BE;
Inventors:
Cheng Yi Chen, Schaffhausen, CH;
Oliver Floegel, Zürich, CH;
Michael Justus, Schaffhausen, CH;
Adrian Maurer, Schaffhausen, CH;
Karl Reuter, Gundelfingen, DE;
Tobias Strittmatter, Schaffhausen, CH;
Tobias Wedel, Karlsruhe, DE;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 309/23 (2006.01); C07C 309/19 (2006.01); C07C 225/20 (2006.01);
U.S. Cl.
CPC ...
C07C 309/23 (2013.01); C07C 225/20 (2013.01); C07C 309/19 (2013.01); C07B 2200/07 (2013.01); C07B 2200/13 (2013.01); C07C 2601/14 (2017.05); C07C 2602/42 (2017.05); H05K 999/99 (2013.01);
Abstract
The present invention is directed to processes for the preparation of esketamine. The present invention is further directed to processes for the resolution of S-ketamine from a racemic or enantiomerically enriched mixture of ketamine. The present invention is further directed to an (S)-CSA salt of S-ketamine, more particularly a monohydrate form of the (S)-CSA salt of S-ketamine; and to an (R)-CSA salt of R-ketamine.