The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2020

Filed:

Apr. 09, 2019
Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

Dominik J. Naczynski, Wallington, NJ (US);

Mei-Chee Tan, Singapore, SG;

Richard E. Riman, Piscataway, NJ (US);

Charles Roth, Princeton, NJ (US);

Prabhas V. Moghe, Basking Ridge, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61B 5/00 (2006.01); A61B 5/055 (2006.01); A61B 6/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0065 (2013.01); A61B 5/0075 (2013.01); A61K 49/0019 (2013.01); A61K 49/0093 (2013.01); A61B 5/055 (2013.01); A61B 6/481 (2013.01); A61B 6/5247 (2013.01);
Abstract

Disclosed is a method of non-invasive infrared imaging, comprising (a) administering a composition containing infrared-emitting particles which contain rare earth elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles; and (b) irradiating with infrared radiation, where both excitation and emission spectra of the encapsulated particles are in the infrared region. Analogous methods of image-guided biomedical intervention, and drug tracking and delivery are also disclosed. Also disclosed is a composition for biomedical applications, containing infrared-emitting particles which contain rare earth-elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles.


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