The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Jul. 31, 2012
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
David J. Yang, Sugar Land, TX (US);
Dongfang Yu, Pearland, TX (US);
Andrew S. Thompson, Mountainside, NJ (US);
F. David Rollo, Saratoga, CA (US);
David J. Yang, Sugar Land, TX (US);
Dongfang Yu, Pearland, TX (US);
Andrew S. Thompson, Mountainside, NJ (US);
F. David Rollo, Saratoga, CA (US);
The Board of Regents of the University of Texas System, Austin, TX (US);
Cell>Point, LLC, Spring, TX (US);
Abstract
Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.