The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Dec. 04, 2018
Hisamitsu Pharmaceutical Co., Inc., Tosu-shi, JP;
Masayuki Suzuki, Tsukuba, JP;
Hiroaki Okutsu, Tsukuba, JP;
Takashi Yasukochi, Tsukuba, JP;
Yasunori Takada, Tsukuba, JP;
HISAMITSU PHARMACEUTICAL CO., INC., Tosu-shi, JP;
Abstract
A method for producing a patch including a support layer, and an adhesive agent layer formed on the support layer and including sodium diacetate, a pressure-sensitive adhesive base agent, and asenapine and/or a pharmaceutically acceptable salt thereof. The sodium diacetate is generated from sodium acetate in the presence of the asenapine and/or salt thereof, a content of the asenapine and/or salt thereof in terms of free asenapine in the adhesive agent layer is in range of 3.0 to 20 mg, and when a content of the asenapine and/or salt thereof in terms of free asenapine in the adhesive agent layer is 6.4 mg and the patch is in contact with skin for 24 hours, Cof free asenapine is in range of 0.5 to 6.0 ng/mL and tof free asenapine is in range of 8 to 28 hr.