The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2020

Filed:

Feb. 28, 2017
Applicant:

Trustees of Tufts College, Medford, MA (US);

Inventors:

Rajendra Kumar-Singh, Boston, MA (US);

Derek Leaderer, Boston, MA (US);

Siobhan Cashman, Boston, MA (US);

Assignee:

Trustees of Tufts College, Medford, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); A61P 37/00 (2006.01); A47K 7/02 (2006.01); B08B 7/02 (2006.01); B25G 1/04 (2006.01); B25G 1/06 (2006.01); A61K 45/06 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A47K 7/026 (2013.01); A61K 45/06 (2013.01); A61P 37/00 (2018.01); B08B 7/02 (2013.01); B25G 1/04 (2013.01); B25G 1/06 (2013.01); C07K 14/70596 (2013.01); G01N 33/6893 (2013.01); G01N 2333/4716 (2013.01);
Abstract

Compositions, methods and kits are provided for treating complement related disorders in a subject with protein in combination having protein fusions of at least two of a CD46 protein, a CD55 protein and a CD59 protein or with a recombinant chimeric protein having at least two of a CD46 protein, a CD55 protein and a CD59 protein or with nucleic acids encoding these proteins. The composition negatively modulates classical and alternative complement pathways thereby treating complement related disorder such as macular degeneration, age-related macular degeneration, diabetic retinopathy, inflammatory bowel disease, thyroiditis, cryoglobulinaemia, fetal loss, organ graft rejection, cancer, etc.


Find Patent Forward Citations

Kumar-Singh, Rajendra. (2020). Compositions, methods and kits for treating complement related disorders (U.S. Patent No. 10813977). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10813977

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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