The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
May. 31, 2019
Applicant:
Decibel Therapeutics, Inc., Boston, MA (US);
Inventors:
John Lee, Arlington, MA (US);
John R. Soglia, Sherborn, MA (US);
Qi-Ying Hu, Needham, MA (US);
Fuxin Shi, Winchester, MA (US);
Assignee:
Decibel Therapeutics, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/04 (2006.01); A61K 9/00 (2006.01); A61P 27/16 (2006.01); A61K 47/36 (2006.01); A61K 33/243 (2019.01);
U.S. Cl.
CPC ...
A61K 33/04 (2013.01); A61K 9/0004 (2013.01); A61K 9/0046 (2013.01); A61P 27/16 (2018.01); A61K 33/243 (2019.01); A61K 47/36 (2013.01);
Abstract
Disclosed herein are methods for otoprotection against platinum-based antineoplastic agents by administering a thiosulfate salt to a subject in need thereof. Typically, the thiosulfate salt is administered to the subject scheduled to be administered a platinum-based antineoplastic agent within 4 hours. Alternatively, the thiosulfate salt is administered within 7 hours after the administration of a platinum-based neoplastic agent.