The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2020

Filed:

Jan. 23, 2017
Applicants:

The George Washington University, a Congressionally Chartered Not-for-profit Corporation, Washington, DC (US);

Washington University IN St. Louis, St. Louis, MO (US);

Inventors:

Cynthia Dowd, Washington, DC (US);

Audrey Odom, St. Louis, MO (US);

Rachel Edwards, St. Louis, MO (US);

Robert Brothers, Washington, DC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7056 (2006.01); A61K 45/06 (2006.01); A61K 31/122 (2006.01); A61K 31/137 (2006.01); A61K 31/357 (2006.01); A61K 31/366 (2006.01); A61K 31/437 (2006.01); A61K 31/4706 (2006.01); A61K 31/496 (2006.01); A61K 31/65 (2006.01); A61K 31/49 (2006.01); A61K 31/683 (2006.01); A61K 31/519 (2006.01); A61K 31/155 (2006.01); A61P 33/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7056 (2013.01); A61K 31/122 (2013.01); A61K 31/137 (2013.01); A61K 31/155 (2013.01); A61K 31/357 (2013.01); A61K 31/366 (2013.01); A61K 31/437 (2013.01); A61K 31/4706 (2013.01); A61K 31/49 (2013.01); A61K 31/496 (2013.01); A61K 31/519 (2013.01); A61K 31/65 (2013.01); A61K 31/683 (2013.01); A61K 45/06 (2013.01); A61P 33/06 (2018.01); Y02A 50/411 (2018.01);
Abstract

A pharmaceutical composition includes a small molecule and a pharmaceutically acceptable excipient. The small molecule interacts with a deoxyxylulose phosphate reductoisomerase (Dxr). A method for treating or preventing a microbial infection in a subject in need thereof includes administering the pharmaceutical composition. A method for inhibiting the growth of a eukaryotic pathogen includes contacting the eukaryotic pathogen with an effective amount of the pharmaceutical composition.


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