The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Nov. 30, 2016
Applicant:
Trianni, Inc, San Francisco, CA (US);
Inventors:
Matthias Wahl, San Francisco, CA (US);
Bao Duong, San Francisco, CA (US);
Nigel Killeen, San Francisco, CA (US);
Assignee:
TRIANNI, INC., San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C07K 16/00 (2006.01); C12N 15/85 (2006.01); C12N 5/12 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); C07K 16/00 (2013.01); C12N 5/12 (2013.01); C12N 15/11 (2013.01); C12N 15/85 (2013.01); A01K 2217/072 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); A01K 2267/03 (2013.01); C07K 2317/52 (2013.01); C07K 2317/60 (2013.01);
Abstract
The invention provides compositions and methods for enhanced production of immunoglobulin diversity. Specifically, the invention provides compositions and methods for making accessible a B cell receptor repertoire that has not been culled by developmental tolerance mechanisms. The invention also provides transgenic animals, cells, and antibodies resulting from these compositions and methods.