The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Aug. 17, 2016
Applicant:

National Tsing Hua University, Hsinchu, TW;

Inventors:

Lee-Wei Yang, Hsinchu, TW;

Jya-Wei Cheng, Hsinchu, TW;

Hong-Chun Li, Hsinchu, TW;

Cheng-Yu Tsai, Hsinchu, TW;

Hui-Yuan Yu, Hsinchu, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06F 30/20 (2020.01); C07K 7/08 (2006.01); G16C 99/00 (2019.01);
U.S. Cl.
CPC ...
G06F 30/20 (2020.01); C07K 7/08 (2013.01); G16C 99/00 (2019.02);
Abstract

The present invention provides an evaluating system and the use thereof for the efficacy of antimicrobial peptide, which includes the following steps: (a) constructing a peptide by a first input unit, and load the peptide into an aqueous solution for a first time for equilibration; (b) constructing a lipid bilayer by a second input unit, and load the lipid bilayer into an aqueous solution for a second time for equilibration; (c) Using a first processing unit, simulations are carried out for an aqueous system containing an equilibrated peptide from the first input unit and the equilibrated lipid bilayer from the second input unit; (d) calculating the partition free energy of the peptide by a second processing unit; (e) outputting the prediction by an output unit, wherein the output unit is connected with the first processing unit and the second processing unit.


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