The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

May. 28, 2019
Applicant:

Biosensing Instrument Inc., Tempe, AZ (US);

Inventors:

Nguyen Ly, Tempe, AZ (US);

Tianwei Jing, Tempe, AZ (US);

Assignee:

BIOSENSING INSTRUMENT INC., Tempe, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/552 (2014.01); G01N 21/59 (2006.01);
U.S. Cl.
CPC ...
G01N 21/553 (2013.01); C12Q 2565/628 (2013.01); G01N 2021/5903 (2013.01);
Abstract

A system in an embodiment can comprise an optical assembly, an SPR light source, and an SPR camera. The optical assembly in this embodiment can comprise a hemispherical prism comprising a planar top surface configured to support a surface-plasmon-resonance (SPR) sensor; a high numerical aperture (NA) lens; and a housing configured to mount the hemispherical prism and the high NA lens the such that the high NA lens is located distal from the planar top surface of the hemispherical prism. The SPR light source in this embodiment can be configured to emit a low-coherent monochromatic light beam for SPR imaging toward the high NA lens. The SPR camera in this embodiment can be configured to capture an SPR image formed after the low-coherent monochromatic light beam is incident upon and reflected by a metal-coated sample contacting surface of the SPR sensor. Additionally, the high NA lens in this embodiment can be configured to refract the low-coherent monochromatic light beam from the SPR light source toward the hemispherical prism; and the hemispherical prism can be configured to collimate the low-coherent monochromatic light beam, as refracted by the high NA lens, toward the SPR sensor. Other embodiments are disclosed.


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