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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10808247 B1

PDFFull Text
Expired
Date of Patent:
Oct. 20, 2020

Filed:

Jul. 06, 2016

Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach

Applicants:

Phio Pharmaceuticals Corp., Marlborough, MA (US);

Synaerion Therapeutics, Berwyn, PA (US);

Inventors:

Michael Byrne, Natick, MA (US);

Antonella Favit-VanPelt, Norwell, MA (US);

Assignees:

Phio Pharmaceuticals Corp., Marlborough, MA (US);

Synaerion Therapeutics, Berwyn, PA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Jane J Zara

Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); A61P 25/28 (2006.01); A61K 31/713 (2006.01); A61K 31/36 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/713 (2013.01); A61P 25/28 (2018.01); C12N 15/111 (2013.01); A61K 31/36 (2013.01); A61K 31/444 (2013.01); A61K 2300/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2320/31 (2013.01);
Abstract

In one aspect, the disclosure provides methods for treating a neurodegenerative disorder, comprising administering to a subject in need thereof a therapeutically effective amount of a nucleic acid molecule and a therapeutically effective amount of a small molecule that activates NF-κB p65 and increases expression of manganese superoxide dismutase (MnSOD/SOD2) and/or expression of a related protein or enzyme.

Find Patent Forward Citations

Byrne, Michael. (2020). Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach (U.S. Patent No. 10808247). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10808247

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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