The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2020
Filed:
Feb. 27, 2018
Applicant:
Translate Bio, Inc., Cambridge, MA (US);
Inventors:
Jonathan Abysalh, Cambridge, MA (US);
Daniel Crawford, Cambridge, MA (US);
Frank DeRosa, Cambridge, MA (US);
Shrirang Karve, Cambridge, MA (US);
Anusha Dias, Cambridge, MA (US);
Michael Heartlein, Cambridge, MA (US);
Assignee:
Translate Bio, Inc., Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); B01L 3/00 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1017 (2013.01); B01L 3/502753 (2013.01); C12Q 1/6806 (2013.01); B01L 2200/028 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0681 (2013.01); B01L 2400/0409 (2013.01); C12Q 2523/113 (2013.01); C12Q 2523/308 (2013.01); C12Y 201/03003 (2013.01);
Abstract
The present invention relates, in part, to methods for large-scale purification of mRNA. The method includes, at least, steps of forming an mRNA slurry, stirring the slurry, and vacuum or pressure filtering the slurry.