The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

May. 15, 2017
Applicant:

Exosome Diagnostics, Inc., Waltham, MA (US);

Inventors:

Georg Stoll, Waltham, MA (US);

Daniel Enderle, Waltham, MA (US);

Mikkel Noerholm, Martinsried, DE;

Johan Karl Olov Skog, Charlestown, MA (US);

Assignee:

Exosome Diagnostics, Inc., Waltham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 15/11 (2006.01); C07H 1/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1006 (2013.01); C12N 15/11 (2013.01); C07H 1/06 (2013.01);
Abstract

The invention provides novel methods and kits for fully automated high-throughput method for isolation of extracellular vesicles and co-isolation of cell-free DNA from biofluids, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, novel methods and kits for isolation of extracellular vesicles and co-isolation of cell-free DNA from biofluids, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles that do not require the use of phenol or chloroform, and for extracting nucleic acids from the extracellular vesicles and/or from the biological samples.


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