The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Dec. 23, 2014
Applicant:

Flir Detection, Inc., Pittsburgh, PA (US);

Inventors:

Jeremy P. Walker, Oakmont, PA (US);

David C. Wilson, Monroeville, PA (US);

Anna M. Leech, Pittsburgh, PA (US);

Jessica J. Sinclair, Murrysville, PA (US);

Assignee:

FLIR DETECTION, INC., Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/96 (2006.01); C12N 11/08 (2020.01); C12N 9/00 (2006.01); C12N 9/16 (2006.01); C12N 9/20 (2006.01); C12N 9/88 (2006.01); C12Q 1/54 (2006.01); A61K 31/74 (2006.01); A61K 31/785 (2006.01); C07K 14/765 (2006.01); A61K 31/79 (2006.01); A61K 47/58 (2017.01); C08F 122/38 (2006.01); C12N 9/04 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/96 (2013.01); A61K 31/74 (2013.01); A61K 31/785 (2013.01); A61K 31/79 (2013.01); A61K 47/58 (2017.08); C07K 14/765 (2013.01); C08F 122/38 (2013.01); C12N 9/0006 (2013.01); C12N 9/16 (2013.01); C12N 9/20 (2013.01); C12N 9/88 (2013.01); C12N 11/08 (2013.01); C12Q 1/54 (2013.01); A61K 38/00 (2013.01); G01N 2333/904 (2013.01);
Abstract

The present invention provides a biomolecule conjugate having one or more functionalized biomolecules wherein the biomolecule is functionalized with one or more reactive sites, and at least one polymer capable of undergoing a polymer growth reaction, wherein the polymer is attached to at least one of the reactive sites of the functionalized biomolecule and wherein the polymer envelopes the functionalized biomolecule to form a reversible nanoparticle structure which protects the biomolecule by dynamically collapsing to preserve the biomolecule when an adverse environmental stimulus is present. A method of protecting a biomolecule from environmental conditions is also provided.


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