The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Feb. 14, 2018
Applicant:

Ablynx NV, Zwijnaarde, BE;

Inventors:

Christine Knuehl, Darmstadt, DE;

Bjoern Hock, Maintal, DE;

Robert Hofmeister, Scituate, MA (US);

Gerald Beste, Ghent, BE;

Hilde Adi Pierrette Revets, Meise, BE;

Frank Kamiel Delphina Verdonck, Sint-Gillis-Waas, BE;

Sigrid Godelieve Victor Cornelis, Sint-Martens-Latem, BE;

Assignee:

Ablynx NV, Zwijnaarde, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/18 (2006.01); C07K 16/32 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61P 35/00 (2018.01); C07K 16/18 (2013.01); C07K 16/32 (2013.01); A61K 2039/505 (2013.01); C07K 2317/22 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present disclosure relates to amino acid sequences that are directed against (as defined herein) HER3, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences (also referred to herein as 'amino acid sequences of the invention', 'compounds of the invention', and “polypeptides of the invention”, respectively). The disclosure also relates to nucleic acids encoding such amino acid sequences and polypeptides (also referred to herein as “nucleic acids of the invention” or “nucleotide sequences of the invention”); to methods forpreparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid sequences or polypeptides; to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells; and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes, such as the prophylactic, therapeutic or diagnostic purposes mentioned herein.


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