The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2020
Filed:
Aug. 16, 2019
Vanderbilt University, Nashville, TN (US);
Rocco D. Gogliotti, Kingston Springs, TN (US);
Shaun R. Stauffer, Brentwood, TN (US);
KyuOk Jeon, Nashville, TN (US);
James M. Salovich, Nashville, TN (US);
Jonathan D. Macdonald, Nashville, TN (US);
Jonathan J. Mills, Nashville, TN (US);
Kenneth M. Meyers, Nashville, TN (US);
Joseph R. Alvarado, Cleveland Heights, OH (US);
Changho Han, Nashville, TN (US);
Stephen W. Fesik, Nashville, TN (US);
Taekyu Lee, Brentwood, TN (US);
Vanderbilt University, Nashville, TN (US);
Abstract
Benzamides and picolinamides that are meta-substituted with imino-, guanidino-, or heterocycle-containing groups disrupt the WDR5-MLL1 protein-protein interaction, and have use in pharmaceutical compositions and in treating proliferative disorders and conditions in a subject, such as cancer.