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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10807948 B1

PDFFull Text
Date of Patent:
Oct. 20, 2020

Filed:

Mar. 04, 2016

Aromatic compounds and uses thereof

Applicant:

Peloton Therapeutics, Inc., Dallas, TX (US);

Inventors:

Darryl David Dixon, Somerset, NJ (US);

Jonas Grina, Coppell, TX (US);

John A. Josey, Dallas, TX (US);

James P. Rizzi, Irving, TX (US);

Stephen T. Schlachter, Dallas, TX (US);

Eli M. Wallace, Richardson, TX (US);

Bin Wang, Dallas, TX (US);

Paul Wehn, Dallas, TX (US);

Rui Xu, Dallas, TX (US);

Hanbiao Yang, Coppell, TX (US);

Assignee:

PELOTON THERAPEUTICS, INC., Dallas, TX (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Paul A Zucker

Int. Cl.
CPC ...
C07C 317/22 (2006.01); C07C 317/24 (2006.01); C07C 255/47 (2006.01); C07C 255/54 (2006.01); C07C 317/36 (2006.01); C07C 317/38 (2006.01); C07C 317/44 (2006.01); C07C 43/23 (2006.01); C07C 217/58 (2006.01); C07C 43/295 (2006.01); C07C 35/00 (2006.01); C07C 323/65 (2006.01); C07C 317/32 (2006.01); C07C 317/46 (2006.01); C07D 213/74 (2006.01); C07D 309/10 (2006.01); C07D 213/85 (2006.01); C07D 309/14 (2006.01); C07D 221/04 (2006.01); C07D 335/02 (2006.01); C07D 249/04 (2006.01); C07D 249/08 (2006.01); C07D 231/14 (2006.01); C07D 333/20 (2006.01); C07D 231/56 (2006.01); C07C 235/40 (2006.01); C07D 207/12 (2006.01); C07C 251/42 (2006.01); C07D 207/48 (2006.01); C07D 209/12 (2006.01); C07D 211/42 (2006.01); C07D 295/096 (2006.01); C07D 211/44 (2006.01); C07D 211/76 (2006.01); C07D 211/96 (2006.01); C07D 213/30 (2006.01); C07D 213/52 (2006.01); C07D 305/06 (2006.01); C07D 305/14 (2006.01); C07D 307/20 (2006.01); C07D 307/52 (2006.01); A61P 35/00 (2006.01); C07D 211/94 (2006.01); C07D 213/89 (2006.01); C07D 265/30 (2006.01); C07D 305/08 (2006.01);
U.S. Cl.
CPC ...
C07C 317/22 (2013.01); A61P 35/00 (2018.01); C07C 43/23 (2013.01); C07C 43/295 (2013.01); C07C 217/58 (2013.01); C07C 235/40 (2013.01); C07C 251/42 (2013.01); C07C 255/47 (2013.01); C07C 255/54 (2013.01); C07C 317/24 (2013.01); C07C 317/32 (2013.01); C07C 317/36 (2013.01); C07C 317/38 (2013.01); C07C 317/44 (2013.01); C07C 317/46 (2013.01); C07C 323/65 (2013.01); C07D 207/12 (2013.01); C07D 207/48 (2013.01); C07D 209/12 (2013.01); C07D 211/42 (2013.01); C07D 211/44 (2013.01); C07D 211/76 (2013.01); C07D 211/94 (2013.01); C07D 211/96 (2013.01); C07D 213/30 (2013.01); C07D 213/52 (2013.01); C07D 213/74 (2013.01); C07D 213/85 (2013.01); C07D 213/89 (2013.01); C07D 221/04 (2013.01); C07D 231/14 (2013.01); C07D 231/56 (2013.01); C07D 249/04 (2013.01); C07D 249/08 (2013.01); C07D 265/30 (2013.01); C07D 295/096 (2013.01); C07D 305/06 (2013.01); C07D 305/08 (2013.01); C07D 305/14 (2013.01); C07D 307/20 (2013.01); C07D 307/52 (2013.01); C07D 309/10 (2013.01); C07D 309/14 (2013.01); C07D 333/20 (2013.01); C07D 335/02 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); C07C 2601/16 (2017.05); C07C 2602/08 (2017.05);
Abstract

Disclosed herein are substituted indane derivatives useful as HIF-2α inhibitors. Pharmaceutical compositions comprising said indane derivatives and methods of using said indane derivatives for treating proliferative diseases, such as renal cell carcinoma and von Hippel-Lindau disease, and other conditions associated with HIF-2α activity are also disclosed.

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Dixon, Darryl. (2020). Aromatic compounds and uses thereof (U.S. Patent No. 10807948). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10807948

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