The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Aug. 16, 2018
Applicant:

The University of Sydney, New South Wales, AU;

Inventors:

Tristan Reekie, New South Wales, AU;

Michael Scott, New South Wales, AU;

Michael Kassiou, New South Wales, AU;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 37/50 (2006.01); C07C 39/15 (2006.01); C07D 311/58 (2006.01); C07D 311/80 (2006.01); C07D 311/94 (2006.01);
U.S. Cl.
CPC ...
C07C 37/50 (2013.01); C07C 39/15 (2013.01); C07D 311/58 (2013.01); C07D 311/80 (2013.01); C07D 311/94 (2013.01);
Abstract

Method for decarboxylating a carboxylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C-Calkyl; R2 is selected from the group consisting of: OH or O, and R3 is selected from the group consisting of: a substituted or unsubstituted cyclohexene, a substituted or unsubstituted C-Calkene, or a substituted or unsubstituted C-Cdialkene; or R2 is O, and R2 and R3 together form a ring structure in which R2 is an internal ring atom; wherein the method includes heating a reaction mixture comprising the carboxylated phytocannabinoid compound and a polar aprotic solvent in the presence of a LiCl for a time sufficient to decarboxylate at least a portion of the carboxylated phytocannabinoid compounds and form the phytocannabinoid compound.


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