The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Aug. 28, 2018
Applicant:

Caliber Therapeutics, Inc., New Hope, PA (US);

Inventors:

William R. Baumbach, New Hope, PA (US);

Darren R. Sherman, New Hope, PA (US);

Robert S. Burgermeister, New Hope, PA (US);

Assignee:

Caliber Therapeutics, LLC, New Hope, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 25/10 (2013.01); A61K 31/00 (2006.01); A61K 31/436 (2006.01); A61L 29/16 (2006.01); A61K 9/107 (2006.01); A61L 29/14 (2006.01);
U.S. Cl.
CPC ...
A61M 25/1018 (2013.01); A61K 9/107 (2013.01); A61K 31/00 (2013.01); A61K 31/436 (2013.01); A61L 29/146 (2013.01); A61L 29/16 (2013.01); A61M 25/10 (2013.01); A61M 25/104 (2013.01); A61M 25/1011 (2013.01); A61M 25/10182 (2013.11); A61M 25/10185 (2013.11); A61M 25/10187 (2013.11); A61L 2300/416 (2013.01); A61L 2300/626 (2013.01); A61M 2025/105 (2013.01); A61M 2025/1013 (2013.01); A61M 2025/1075 (2013.01);
Abstract

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.


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