The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Sep. 17, 2015
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

National University of Singapore, Singapore, SG;

Inventors:

Majid Ebrahimi Warkiani, Singapore, SG;

Guofeng Guan, Singapore, SG;

Kah Ping Andy Tay, Singapore, SG;

Lidan Wu, Cambridge, MA (US);

Jongyoon Han, Cambridge, MA (US);

Chwee Teck Lim, Singapore, SG;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2006.01); A61M 1/02 (2006.01);
U.S. Cl.
CPC ...
A61M 1/36 (2013.01); A61M 1/0281 (2013.01); A61M 2202/09 (2013.01); A61M 2202/20 (2013.01); A61M 2205/0244 (2013.01); A61M 2206/10 (2013.01);
Abstract

A system for intra-operative blood salvage autotransfusion is provided. The system comprises at least one inlet configured to receive whole blood of a patient; at least one curvilinear microchannel in fluid flow connection with the at least one inlet, the at least one curvilinear microchannel being adapted to isolate circulating tumor cells in the whole blood, based on cell size, along at least one portion of a cross-section of the at least one curvilinear microchannel; and at least two outlets in fluid flow connection with the at least one curvilinear microchannel, at least one outlet of the at least two outlets being configured to flow the circulating tumor cells isolated from the whole blood, and at least one other outlet of the at least two outlets being configured to flow at least a portion of a remainder of the whole blood, cleansed of the isolated circulating tumor cells, for return to the patient.


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