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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10806805 B1

PDFFull Text
Date of Patent:
Oct. 20, 2020

Filed:

Mar. 03, 2017

Mri and ct contrast-enabled composite implants for image-guided tissue regeneration and therapy

Applicant:

Amrita Vishwa Vidyapeetham, Kochi, IN;

Inventors:

Manzoor Koyakutty, Kochi, IN;

Sajesh K. Meethaleveedu, Kochi, IN;

Anusha Ashokan, Kochi, IN;

Vijay Harish Somasundaram, Kochi, IN;

Shantikumar Nair, Kochi, IN;

Assignee:

Other;

Attorneys:

Convergence Intellectual Property Law P.C.

Jonathan Garfinkel

Primary Examiner:

Micah Paul Young

Int. Cl.
CPC ...
A61L 27/56 (2006.01); A61K 49/18 (2006.01); A61K 9/00 (2006.01); A61L 27/50 (2006.01); A61K 49/00 (2006.01); A61K 49/04 (2006.01); A61L 27/46 (2006.01); A61B 5/055 (2006.01); A61K 49/14 (2006.01); A61L 27/02 (2006.01); A61L 27/20 (2006.01); A61L 27/22 (2006.01); A61L 27/44 (2006.01); A61L 27/54 (2006.01); A61K 47/42 (2017.01); A61K 47/02 (2006.01); G01R 33/58 (2006.01); A61K 47/36 (2006.01); A61K 9/19 (2006.01); A61B 6/00 (2006.01); G01R 33/48 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1818 (2013.01); A61B 5/055 (2013.01); A61K 9/0024 (2013.01); A61K 49/0002 (2013.01); A61K 49/04 (2013.01); A61K 49/0419 (2013.01); A61K 49/0457 (2013.01); A61K 49/14 (2013.01); A61K 49/1803 (2013.01); A61L 27/025 (2013.01); A61L 27/20 (2013.01); A61L 27/222 (2013.01); A61L 27/446 (2013.01); A61L 27/46 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61B 6/481 (2013.01); A61K 9/19 (2013.01); A61K 47/02 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01); A61L 2300/414 (2013.01); A61L 2400/12 (2013.01); A61L 2430/00 (2013.01); A61L 2430/02 (2013.01); G01R 33/4812 (2013.01); G01R 33/5601 (2013.01); G01R 33/58 (2013.01);
Abstract

A composite implant for providing simultaneous magnetic resonance imaging (MRI) and computed tomographic (CT) imaging contrast is disclosed. The composite implant is formed of a calcium compound in the form of nano or microparticles doped with a first dopant configured to provide MRI contrast and a second dopant configured to provide CT contrast. The calcium compound is loaded onto a polymer gel matrix and lyophilized to form a mass with 3-dimensionally interconnected porosity, configured to provide tissue integration and proliferation sites. Methods of forming the composite implant are also disclosed. The implant could be a scaffold or bead structured to enable treatment of human or animal patient for bone/cartilage injury or defect by implantation, with MRI and CT monitoring.

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