The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Aug. 31, 2017
Applicant:

Genopharm Inc., Seoul, KR;

Inventors:

Young Kee Shin, Seoul, KR;

Young Deug Kim, Incheon, KR;

Jun Young Choi, Gwangmyeong-si, KR;

Tae Eun Kim, Anyang-si, KR;

Young Jin Lee, Seoul, KR;

Ju Ho Lee, Seoul, KR;

Yeong Mun Kim, Bucheon-si, KR;

Assignee:

GENOPHARM INC., Seoul, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C07K 14/565 (2006.01); C07K 16/30 (2006.01); C07K 19/00 (2006.01); C12N 15/63 (2006.01); A61K 38/19 (2006.01); A61K 38/21 (2006.01);
U.S. Cl.
CPC ...
A61K 47/642 (2017.08); A61K 47/6813 (2017.08); A61K 47/6845 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6875 (2017.08); C07K 14/565 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); C07K 19/00 (2013.01); C12N 15/63 (2013.01); A61K 38/19 (2013.01); C07K 2317/14 (2013.01); C07K 2317/30 (2013.01); C07K 2319/00 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present invention relates to an immunocytokine in which a human interferon-beta variant is conjugated to an antibody or a fragment thereof, and a method for preparing the same. The human interferon-beta variant has superior activity or functions compared with natural interferon-beta, and the productivity of the immunocytokine according to the present invention is excellent. In addition, the immunocytokine according to the present invention can be favorably used as a target therapeutic agent for multiple sclerosis or cancer since the immunocytokine express both of functions of the interferon-beta and characteristics of the antibody binding to a specific antigen.


Find Patent Forward Citations

Loading…