The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2020
Filed:
May. 29, 2018
Applicant:
Shanghai Lumosa Therapeutics Co., Ltd., Shanghai, CN;
Inventors:
Assignee:
Shanghai Lumosa Therapeutics Co., Ltd., Shanghai, CN;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); C07K 7/06 (2006.01); C07K 5/09 (2006.01); C07K 5/083 (2006.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); A61K 47/69 (2017.01); A61K 38/00 (2006.01); C07K 5/097 (2006.01); A61K 31/4164 (2006.01); A61K 38/08 (2019.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
A61K 47/64 (2017.08); A61K 31/4164 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); A61K 38/08 (2013.01); A61K 47/542 (2017.08); A61K 47/6929 (2017.08); C07K 5/0806 (2013.01); C07K 5/0815 (2013.01); C07K 5/0821 (2013.01); C07K 7/06 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention discloses a novel compound with effects of thrombolysis, free radical scavenging and thrombus-targeting, as well as a preparation method and use thereof. The compound is a ternary conjugate formed by conjugating a thrombolytic peptide, a free radical scavenger and a thrombus-targeting/antithrombotic peptide together via a linking arm. The present invention also discloses a pharmaceutical composition containing the compounds, wherein the compounds form a nanospherical structure.