The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2020
Filed:
Aug. 21, 2018
Applicant:
Nektar Therapeutics, San Francisco, CA (US);
Inventors:
C. Simone Jude-Fishburn, Redwood City, CA (US);
Laurie A. VanderVeen, San Mateo, CA (US);
Timothy A. Riley, Worcester, MA (US);
Assignee:
Nektar Therapeutics, San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01); A61K 31/34 (2006.01); A61K 47/55 (2017.01); A61K 31/4402 (2006.01); A61K 31/4433 (2006.01); A61K 31/635 (2006.01); A61K 38/05 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 31/4402 (2013.01); A61K 31/4433 (2013.01); A61K 31/635 (2013.01); A61K 38/05 (2013.01); A61K 47/60 (2017.08);
Abstract
Provided herein (among other things) are protease inhibitor compounds having enhanced features, along with methods for administering such compounds. For example, the subject compounds can be administered without concomitant administration of a CYP3A4 inhibitor, have increased therapeutic index and/or increased potency, and are low-resistance inducing in nature.