The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2020

Filed:

Feb. 16, 2016
Applicant:

Pharma Foods International Co., Ltd., Kyoto, JP;

Inventors:

Chie Kudo, Tokyo, JP;

Masayoshi Toyoura, Kyoto, JP;

Akiko Ishida, Kyoto, JP;

Yuji Shoya, Kyoto, JP;

Chihiro Yamazaki, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01); A61K 31/675 (2006.01); C12N 15/09 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/395 (2013.01); A61K 31/675 (2013.01); A61K 39/39533 (2013.01); A61K 45/06 (2013.01); C07K 16/18 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/23 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 15/09 (2013.01);
Abstract

The present invention provides an anti-FSTL1 antibody or a fragment or functional equivalent thereof, wherein the antibody recognizes an epitope in a region selected from the group consisting of amino acid positions 48 to 100, 148 to 162, 193 to 216, 205 to 228, and 272 to 289 of SEQ ID NO: 1 (amino acid sequence of human FSTL1). The present invention also provides a combination product of a FSTL1 suppressor and additional cancer treatment. It is understood that immune defect such as immunosuppression or immunodeficiency is effectively mitigated by the present invention.


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