The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2020
Filed:
May. 09, 2016
Applicant:
Katholieke Universiteit Leuven, Leuven, BE;
Inventors:
Frauke Christ, Heverlee, BE;
Zeger Debyser, Heverlee, BE;
Rik Gijsbers, Blanden, BE;
Lenard Vranckx, Hulshout, BE;
Assignee:
Katholieke Universiteit Leuven, Leuven, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12P 19/34 (2006.01); A61K 31/505 (2006.01); A61K 45/06 (2006.01); A61K 31/44 (2006.01); A61K 31/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/505 (2013.01); A61K 31/00 (2013.01); A61K 31/44 (2013.01); A61K 45/06 (2013.01); A61K 48/005 (2013.01); C12N 2740/16043 (2013.01);
Abstract
The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy.