The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2020

Filed:

Feb. 03, 2014
Applicant:

Hitachi High-technologies Corporation, Tokyo, JP;

Inventors:

Koshin Hamasaki, Tokyo, JP;

Toshiro Saito, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 33/543 (2006.01); B01L 3/00 (2006.01); G01N 27/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54333 (2013.01); B01L 3/50273 (2013.01); G01N 21/6428 (2013.01); G01N 21/6486 (2013.01); G01N 33/5434 (2013.01); G01N 33/54326 (2013.01); G01N 33/54346 (2013.01); G01N 27/745 (2013.01); G01N 2021/6439 (2013.01);
Abstract

Paramagnetic fine particles of 1 micron or less used under a strong magnetic field were shown to form beads-like aggregates along the magnetic flux, and become irregularly shaped as such a mass of particles combines with a flat particle layer. This phenomenon becomes a factor that degrades the quality of quantification in bioanalysis. By confining a solution of microscopic magnetic fine particles between flat substrates of high wettability as thin a vertical thickness as possible and attracting the magnetic fine particles under a magnetic field applied from the side of one of the flat substrates, the magnetic fine particles can be evenly immobilized in the form of a film on the substrate surface in a dispersion state, and the quality of the biomolecule quantification can be improved.


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