The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2020

Filed:

Mar. 31, 2017
Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

Joshua Robert Leeman, Winchester, MA (US);

Randal Byrn, Wayland, MA (US);

Hamilton Barlow Bennett, Malden, MA (US);

Douglas John Bartels, North Liberty, IA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C07K 14/005 (2006.01); C07K 16/10 (2006.01); C07K 16/40 (2006.01); C12N 7/00 (2006.01); C12N 9/12 (2006.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/701 (2013.01); C07K 14/005 (2013.01); C07K 16/1018 (2013.01); C07K 16/40 (2013.01); C12N 7/00 (2013.01); C12N 9/1241 (2013.01); C12Q 1/025 (2013.01); C12Y 207/07 (2013.01); G01N 33/5008 (2013.01); C07K 2317/34 (2013.01); C12N 2760/16121 (2013.01); C12N 2760/16122 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/11 (2013.01); G01N 2333/91245 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to influenza A virus variants, particularly variants that are resistant to a polymerase inhibitors. Also provided are methods and compositions related to the influenza A virus variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.


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