The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2020
Filed:
Nov. 18, 2016
Applicant:
Orbis Health Solutions, Llc, Greenville, SC (US);
Inventor:
Thomas E. Wagner, Greenville, SC (US);
Assignee:
Orbis Health Solutions, LLC, Greenville, SC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61P 37/04 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); C07K 14/005 (2006.01); C12N 5/074 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61P 37/04 (2018.01); C07K 14/005 (2013.01); C12N 5/0696 (2013.01); A61K 2039/53 (2013.01); A61K 2039/876 (2018.08); C12N 2501/20 (2013.01); C12N 2760/16034 (2013.01); C12N 2770/36134 (2013.01); C12N 2770/36143 (2013.01); C12N 2770/36151 (2013.01); C12N 2770/36152 (2013.01); C12N 2795/10222 (2013.01); C12N 2830/00 (2013.01); C12N 2840/203 (2013.01);
Abstract
The present invention relates generally to a gene expression system utilizing an alphavirus replicon and T7 promoter. The system is capable of expressing proteins in the cell cytoplasm without integrating the gene of interest into the genome of a host cell. The invention has a wide range of applications such as producing induced pluripotent cells and vaccines against pathogens and cancers.