The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2020
Filed:
Dec. 18, 2015
Applicant:
Cytomx Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Herman Waldmann, Oxford, GB;
Mark Raymond Frewin, Oxford, GB;
Lisa Kim Gilliland, Balemo, GB;
Luis Richardo Simoes Da Silva Graca, Oxford, GB;
Assignee:
CytomX Therapeutics, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2893 (2013.01); A61K 47/6849 (2017.08); C07K 14/70592 (2013.01); C07K 16/28 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/41 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/56 (2013.01); C07K 2318/10 (2013.01); C07K 2319/00 (2013.01);
Abstract
A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.