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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10800821 B1

PDFFull Text
Date of Patent:
Oct. 13, 2020

Filed:

Nov. 16, 2015

Recombinant bi-functional fusion protein and preparation and application therefor

Applicant:

Immuneonco Biopharmaceuticals (Shanghai) Co., Ltd, Shanghai, CN;

Inventors:

Wenzhi Tian, Shanghai, CN;

Deqiang Jing, Shanghai, CN;

Assignee:

IMMUNEONCO BIOPHARMACEUTICALS (SHANGHAI) CO., LTD, Shanghai, CN;

Attorneys:

Duane Morris LLP

Thomas J. Kowalski

Deborah L. Lu

Primary Examiner:

Michael Allen

Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 19/00 (2006.01); C07K 14/47 (2006.01); C12N 5/10 (2006.01); A61K 39/395 (2006.01); C12N 15/63 (2006.01); C12N 15/62 (2006.01); A61P 11/06 (2006.01); A61P 19/02 (2006.01); A61P 35/02 (2006.01); A61P 1/00 (2006.01); A61P 35/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 39/395 (2013.01); A61P 1/00 (2018.01); A61P 11/06 (2018.01); A61P 19/02 (2018.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/74 (2013.01);
Abstract

The present invention provides a recombinant fusion protein containing a first extracellular Ig-like domain of a signal-regulator protein alpha (SIRPα), linked to an Fc fragment of a human IgG1. The present invention also provides a polynucleotide encoding the recombinant fusion protein, an expression vector containing the polynucleotide, a method for producing the recombinant protein and a method for treating a disease caused by over expression of CD47.

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Tian, Wenzhi. (2020). Recombinant bi-functional fusion protein and preparation and application therefor (U.S. Patent No. 10800821). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10800821

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