The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2020
Filed:
Nov. 16, 2017
Baxalta Gmbh, Glattpark, (Opfikon), CH;
Baxalta Incorporated, Bannockburn, IL (US);
Michael Dockal, Vienna, AT;
Rudolf Hartmann, Bisamberg, AT;
Friedrich Scheiflinger, Vienna, AT;
Frank Osterkamp, Berlin, DE;
Thomas Polakowski, Berlin, DE;
Ulrich Reineke, Berlin, DE;
Baxalta GmbH, Glattpark, (Opfikon), CH;
Baxalta Incorporated, Bannockburn, IL (US);
Abstract
The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. Peptide complexes also are provided. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, treat a blood coagulation disorder in a subject, purify TFPI, and identify a TFPI-binding compound.