The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2020

Filed:

Oct. 25, 2018
Applicants:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Hydra Biosciences, Llc, Belmont, MA (US);

Inventors:

Thierry Bouyssou, Ingelheim am Rhein, DE;

Dirk Gottschling, Ingelheim am Rhein, DE;

Niklas Heine, Ingelheim am Rhein, DE;

Lana Louise Smith Keenan, Poughquag, NY (US);

Michael D. Lowe, Pleasantville, NY (US);

Hossein Razavi, Danbury, CT (US);

Christopher Ronald Sarko, San Ramon, CA (US);

Simon Surprenant, Boisbriand, CA;

Hidenori Takahashi, LaGrangeville, NY (US);

Michael Robert Turner, Danbury, CT (US);

Xinyuan Wu, Newton, MA (US);

Assignees:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Hydra Biosciences, LLC, Belmont, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4412 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/501 (2006.01); A61P 9/00 (2006.01); C07D 401/14 (2006.01); C07D 451/02 (2006.01); C07D 487/08 (2006.01); C07D 498/08 (2006.01); C07D 213/04 (2006.01); A61K 31/45 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/45 (2013.01); A61K 31/501 (2013.01); C07D 213/04 (2013.01); C07D 451/02 (2013.01); C07D 487/08 (2013.01); C07D 498/08 (2013.01);
Abstract

The invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein Rto R, A, Y and L are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.


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