The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2020
Filed:
Aug. 21, 2014
Applicant:
Virginia Commonwealth University, Richmond, VA (US);
Inventors:
Martin Safo, Richmond, VA (US);
Jurgen Venitz, Richmond, VA (US);
Richmond Danso-Danquah, Henrico, VA (US);
Tanvi Deshpande, Baltimore, MD (US);
Yan Zhang, Glen Allen, VA (US);
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/58 (2006.01); C07D 213/30 (2006.01);
U.S. Cl.
CPC ...
C07D 307/58 (2013.01); C07D 213/30 (2013.01);
Abstract
The invention provides new aromatic aldehyde compounds that have greater potency in increasing the affinity of Hb for oxygen, greater potency for preventing sickling, and additional pharmacologic properties that ameliorate other symptoms of SCD. The invention further provides methods for treating SCD by providing a subject having SCD with a compound according to the invention.