The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2020

Filed:

Dec. 07, 2015
Applicants:

Osaka University, Osaka, JP;

Tohoku University, Miyagi, JP;

Inventors:

Mitsuru Akashi, Suita, JP;

Michiya Matsusaki, Toyonaka, JP;

Michiaki Unno, Sendai, JP;

Naoaki Sakata, Sendai, JP;

Gumpei Yoshimatsu, Sendai, JP;

Assignees:

OSAKA UNIVERSITY, Osaka, JP;

TOHOKU UNIVERSITY, Miyagi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); A61K 35/44 (2015.01); A61K 35/39 (2015.01); A61L 27/36 (2006.01); C12N 5/071 (2010.01); A61L 27/60 (2006.01); A61K 35/28 (2015.01); A61K 35/36 (2015.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3804 (2013.01); A61K 35/39 (2013.01); A61K 35/44 (2013.01); A61L 27/3633 (2013.01); A61L 27/3834 (2013.01); A61L 27/3886 (2013.01); A61L 27/60 (2013.01); C12N 5/069 (2013.01); C12N 5/0697 (2013.01); A61K 35/28 (2013.01); A61K 35/36 (2013.01); C12N 5/00 (2013.01); C12N 2502/1323 (2013.01); C12N 2502/1358 (2013.01); C12N 2502/22 (2013.01); C12N 2503/04 (2013.01); C12N 2533/52 (2013.01); C12N 2533/90 (2013.01);
Abstract

An artificial tissue containing pancreatic islet cells, fibroblasts and/or cells capable of differentiating, extracellular matrix, and vascular endothelial cells, in which the fibroblasts and/or the cells capable of differentiating, the extracellular matrix, and the vascular endothelial cells constitute a three-dimensional tissue structure in which a vascular network structure has been formed, and in which the three-dimensional tissue structure contains pancreatic islets constituted by aggregating ten or more of the pancreatic islet cells.


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