The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2020

Filed:

Jan. 15, 2016
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Tzyy-Choou Wu, Stevenson, MD (US);

Chien-Fu Hung, Timonium, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/00 (2006.01); C07K 14/47 (2006.01); A61K 38/17 (2006.01); A61K 47/64 (2017.01); A61K 9/00 (2006.01); A61K 33/24 (2019.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 9/0019 (2013.01); A61K 33/24 (2013.01); A61K 38/1709 (2013.01); A61K 39/0011 (2013.01); A61K 47/643 (2017.08); A61K 47/646 (2017.08); C07K 14/4721 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55516 (2013.01); C07K 2319/40 (2013.01); C07K 2319/50 (2013.01);
Abstract

Described herein are methods comprising administering to a mammalian subject an effective amount of an annexin chimeric fusion protein, wherein the annexin chimeric fusion protein comprises at least one immunogenic antigen, thereby enhancing the antigen specific immune response relative to administration of the immunogenic antige alone. Methods and kits for treating or preventing recurrence of hyper proliferating diseases, e.g., cancer, are described. A method may comprise priming a mammal by administering to the mammal an effective amount of a chemotherapeutic agent and boosting the mammal by administering to the mammal an effective amount of an annexin chimeric fusion.


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