The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2020

Filed:

Feb. 01, 2018
Applicant:

Ai Therapeutics, Inc., Guilford, CT (US);

Inventors:

Neil Beeharry, Guilford, CT (US);

Marylens Hernandez, Guilford, CT (US);

Sean Landrette, Meriden, CT (US);

Tian Xu, Guilford, CT (US);

Jonathan M. Rothberg, Guilford, CT (US);

Henri Lichenstein, Guilford, CT (US);

Assignee:

A1 Therapeutics, Inc., Guilford, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); A61K 31/496 (2006.01); A61K 31/437 (2006.01); A61K 31/46 (2006.01); A61P 35/02 (2006.01); A61K 31/416 (2006.01); A61P 35/00 (2006.01); A61K 31/444 (2006.01); A61K 31/635 (2006.01); A61K 31/395 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/52 (2013.01); A61K 31/395 (2013.01); A61K 31/416 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/46 (2013.01); A61K 31/496 (2013.01); A61K 31/635 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); A61K 2300/00 (2013.01);
Abstract

The disclosure also provides compositions and methods related to combination therapy with HSP90 inhibitors and BCL-2 pathway inhibitors for treating cancer. The disclosure also provides compositions and methods related to the use of 'low dose' HSP90 inhibitors in the treatment of cancer, alone and in combination with other therapeutic agents.


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