The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2020

Filed:

Nov. 27, 2015
Applicants:

Fujifilm Wako Pure Chemical Corporation, Osaka-shi, Osaka, JP;

Osaka University, Suita-shi, Osaka, JP;

Inventors:

Takahiro Nishibu, Amagasaki, JP;

Naoko Imawaka, Amagasaki, JP;

Ken Naruse, Amagasaki, JP;

Rikinari Hanayama, Suita, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C07K 1/14 (2006.01); C07K 17/02 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); C12N 15/09 (2006.01); C07K 17/00 (2006.01); C12N 7/02 (2006.01); C07K 14/705 (2006.01); G01N 33/53 (2006.01); G01N 15/00 (2006.01); G01N 15/10 (2006.01); G01N 15/14 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5076 (2013.01); C07K 1/14 (2013.01); C07K 14/70503 (2013.01); C07K 17/00 (2013.01); C07K 17/02 (2013.01); C12N 7/02 (2013.01); C12N 15/09 (2013.01); G01N 33/5432 (2013.01); G01N 33/6842 (2013.01); C07K 2319/40 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/18551 (2013.01); G01N 33/53 (2013.01); G01N 2015/008 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/149 (2013.01);
Abstract

The invention provides a carrier and a method for obtaining, removing, or detecting extracellular membrane vesicle or virus present in a sample. In particular, the invention provides (a) a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; (b) a method for obtaining the extracellular membrane vesicle or the virus in the sample; (c) a method for removing the extracellular membrane vesicle or the virus in the sample; (d) a method for detecting the extracellular membrane vesicle or the virus in the sample; (e) a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and f) a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier.


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