The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2020
Filed:
Aug. 17, 2016
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Viviana Gradinaru, La Canada Flintridge, CA (US);
Jennifer Treweek, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/24 (2006.01); C08L 71/02 (2006.01); B82Y 5/00 (2011.01); G01N 1/30 (2006.01); C12Q 1/6841 (2018.01); C12Q 1/68 (2018.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
G01N 1/30 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6841 (2013.01); C12Q 1/6806 (2013.01);
Abstract
In various embodiments, the present application teaches methods for tissue clearing in which tissues are rendered macromolecule-permeable and optically-transparent, thereby exposing their cellular structure with intact connectivity. In some embodiments, the present application teaches ePACT, which is a protocol for enhanced tissue clearing via expansion. In some embodiments, the present application teaches visualizing a tissue that has been expanded via ePACT.