The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2020

Filed:

Jun. 02, 2017
Applicant:

Quest Diagnostics Investments Llc, Secaucus, NJ (US);

Inventors:

Peter Lee, Tustin, CA (US);

Raymond Huang, Cerritos, CA (US);

Kristin Ramos, Carson, CA (US);

Jules Chen, Irvine, CA (US);

Michelle Tabb, Santa Ana, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/70 (2006.01); G01N 33/569 (2006.01); C12N 7/00 (2006.01); A01N 43/04 (2006.01); A61P 31/14 (2006.01); C12Q 1/686 (2018.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/701 (2013.01); A61P 31/14 (2018.01); C12N 7/00 (2013.01); C12Q 1/68 (2013.01); C12Q 1/686 (2013.01); C12Q 1/70 (2013.01); G01N 33/56983 (2013.01); A61K 39/00 (2013.01); C12N 2770/16021 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); G01N 2333/08 (2013.01);
Abstract

The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.


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