The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2020
Filed:
Nov. 27, 2017
Applicants:
University of Iowa Research Foundation, Iowa City, IA (US);
University of Kansas, Lawrence, KS (US);
Inventors:
Ziying Yan, Iowa City, IA (US);
John F. Engelhardt, Iowa City, IA (US);
Jianming Qiu, Overland Park, KS (US);
Assignees:
University of Iowa Research Foundation, Iowa City, IA (US);
University of Kansas, Lawrence, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/79 (2006.01); A61K 39/23 (2006.01); C07H 21/04 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01); C12N 15/86 (2006.01); C12N 15/864 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 39/00 (2013.01); A61K 39/23 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); C07H 21/04 (2013.01); C07K 14/435 (2013.01); C12N 15/8645 (2013.01); C12N 2750/14111 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14144 (2013.01); C12N 2750/14145 (2013.01); C12N 2750/14322 (2013.01); C12N 2750/14333 (2013.01); C12N 2810/6027 (2013.01);
Abstract
The invention provides an isolated chimeric virus comprising bocavirus capsid protein and a recombinant adeno-associated viral (AAV) genome, an isolated rBoV comprising human bocavirus capsid protein and a recombinant BoV genome, and uses therefor. For example, the chimeric virus may be employed to deliver transgenes, such as those encoding therapeutic or prophylactic gene products, to mammalian cells.