The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2020
Filed:
Apr. 29, 2014
Lawrence Livermore National Security, Llc, Livermore, CA (US);
Heeral Sheth, San Francisco, CA (US);
Haiyin Chen, San Ramon, CA (US);
Bryan D. Hudson, Livermore, CA (US);
Kris Kulp, Livermore, CA (US);
Margaret W. Mcnerney, Pleasanton, CA (US);
Satinderpall S. Pannu, Pleasanton, CA (US);
Fang Qian, Santa Cruz, CA (US);
Angela C. Tooker, Dublin, CA (US);
Elizabeth K. Wheeler, Livermore, CA (US);
Vanessa Tolosa, Emeryville, CA (US);
Lawrence Livermore National Security, LLC, Livermore, CA (US);
Abstract
In one embodiment, a system includes a bioreactor coupled to a substrate. The bioreactor includes: a plurality of walls defining a reservoir; a plurality of fluidic channels in at least some of the walls; a fluidic inlet in fluidic communication with the reservoir via, the fluidic channels; a fluidic outlet in fluidic communication with the reservoir via the fluidic channels; and one or more sensors coupled to the reservoir, each sensor being configured to detect one or more of: environmental conditions in the reservoir; and physiological conditions of one or more cells optionally present in the reservoir. In another embodiment, a method includes delivering media to a reservoir of a bioreactor; delivering a plurality of cells to the reservoir, controlling a reservoir temperature and a reservoir gas composition; using one or more of the sensors to monitor environmental and physiological conditions; and reporting the environmental and/or physiological conditions.