The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2020
Filed:
Jul. 15, 2016
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Kai W. Wucherpfennig, Brookline, MA (US);
Bettina Franz, Orem, UT (US);
Kenneth F. May, Jr., Bozeman, MT (US);
Glenn Dranoff, Sudbury, MA (US);
F. Stephen Hodi, Framingham, MA (US);
Christopher Harvey, Boston, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
The present disclosure provides, in part, compositions comprising peptides that immunospecifically bind to a defined binding partner, such as MHC class I polypeptide-related sequence A (MICA), or an epitope thereon. In some embodiments, the peptides comprise one or more complementarity determining regions relating to the complementarity regions shown in Table 1. The disclosure also provides methods of treating cancer in a subject using the compositions disclosed herein, and methods of isolating human antibodies from cancer patients following immunotherapy.