The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2020
Filed:
Apr. 28, 2017
National University of Singapore, Singapore, SG;
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Agency for Science, Technology and Research, Singapore, SG;
Bee Hui Liu, Singapore, SG;
Daniel Geoffrey Tenen, Singapore, SG;
Li Chai, Boston, MA (US);
Cheng San Brian Chia, Singapore, SG;
Anders Poulsen, Singapore, SG;
National University of Singapore, Singapore, SG;
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Agency for Science, Technology and Research, Singapore, SG;
Abstract
Isolated peptides and pharmaceutical compositions comprising isolated peptides that bind to retinoblastoma binding protein 4 (RBBp4) and block the Spalt-Like Transcription Factor 4 (SALL4)-RBBp4 interaction are described. Methods of inhibiting binding of SALL4 to RBBp4 and methods of treating a subject having a disorder mediated by a dysregulation of SALL4 are also described.