The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10793538 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 06, 2020

Filed:

Jan. 24, 2018
Applicant:

The Broad Institute, Inc., Cambridge, MA (US);

Inventors:

Edward Holson, Newton, MA (US);

Fanny Lazzaro, Cambridge, MA (US);

David Olson, Boston, MA (US);

Florence Fevrier Wagner, Ashland, MA (US);

Michel Weiwer, Cambridge, MA (US);

Assignee:

The Broad Institute, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 309/28 (2006.01); C07C 259/08 (2006.01); C07C 323/61 (2006.01); C07D 209/08 (2006.01); C07D 211/78 (2006.01); C07D 211/96 (2006.01); C07D 263/16 (2006.01);
U.S. Cl.
CPC ...
C07D 309/28 (2013.01); C07C 259/08 (2013.01); C07C 323/61 (2013.01); C07D 209/08 (2013.01); C07D 211/78 (2013.01); C07D 211/96 (2013.01); C07D 263/16 (2013.01); C07C 2601/10 (2017.05); C07C 2601/16 (2017.05); C07C 2602/08 (2017.05); C07C 2602/10 (2017.05);
Abstract

The present invention provides compounds of formula (I): or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and Rare as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.


Find Patent Forward Citations

Holson, Edward. (2020). Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors (U.S. Patent No. 10793538). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10793538

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