The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2020

Filed:

Nov. 11, 2015
Applicant:

Aurimmed Pharma, Inc., Salt Lake City, UT (US);

Inventors:

Amir Pesyan, Park City, UT (US);

Manuel F. Balandrin, Sandy, UT (US);

Assignee:

AURIMMED PHARMA, INC., Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); C07C 237/22 (2006.01); C07C 233/08 (2006.01); C07D 295/033 (2006.01); C07D 295/155 (2006.01); A61K 31/36 (2006.01); A61K 31/495 (2006.01); C07D 295/185 (2006.01); A61K 31/353 (2006.01); A61K 31/445 (2006.01); A61K 31/5375 (2006.01); C07D 211/26 (2006.01); A61K 45/06 (2006.01); A61K 31/44 (2006.01); C07D 213/61 (2006.01); C07D 211/16 (2006.01); C07D 213/56 (2006.01); C07D 213/65 (2006.01); C07C 233/11 (2006.01); C07D 319/18 (2006.01); C07C 235/20 (2006.01); C07C 233/58 (2006.01); C07D 211/60 (2006.01); C07C 255/54 (2006.01); C07C 235/34 (2006.01); C07D 211/62 (2006.01); C07D 317/60 (2006.01); C07D 307/79 (2006.01); C07D 207/16 (2006.01); C07C 235/78 (2006.01);
U.S. Cl.
CPC ...
C07C 233/08 (2013.01); A61K 31/165 (2013.01); A61K 31/353 (2013.01); A61K 31/36 (2013.01); A61K 31/44 (2013.01); A61K 31/445 (2013.01); A61K 31/495 (2013.01); A61K 31/5375 (2013.01); A61K 45/06 (2013.01); C07C 233/11 (2013.01); C07C 233/58 (2013.01); C07C 235/20 (2013.01); C07C 235/34 (2013.01); C07C 235/78 (2013.01); C07C 237/22 (2013.01); C07C 255/54 (2013.01); C07D 207/16 (2013.01); C07D 211/16 (2013.01); C07D 211/26 (2013.01); C07D 211/60 (2013.01); C07D 211/62 (2013.01); C07D 213/56 (2013.01); C07D 213/61 (2013.01); C07D 213/65 (2013.01); C07D 295/033 (2013.01); C07D 295/155 (2013.01); C07D 295/185 (2013.01); C07D 307/79 (2013.01); C07D 317/60 (2013.01); C07D 319/18 (2013.01); C07C 2601/02 (2017.05);
Abstract

A series of novel amides showing broad pharmaceutical activity. Compounds described herein are effective as anticonvulsants, chemical countermeasures, and analgesics. Such compounds also show, neuroprotective/neuroreparative effects and activity against spinal muscular atrophy. Such pharmaceutically active compounds show utility in the treatment of central nervous system ('CNS') diseases and disorders, such as anxiety, depression, insomnia, migraine headaches, schizophrenia, neurodegenerative diseases (e.g., Parkinson's disease, Alzheimer's, ALS, and Huntington's disease) spasticity, and bipolar disorder. Furthermore, such compounds may additionally find utility as analgesics (e.g., for the treatment of chronic or neuropathic pain) and as neuroprotective agents useful in the treatment of stroke(s), and/or traumatic brain and/or spinal cord injuries.


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