The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10792367 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 06, 2020

Filed:

Dec. 01, 2017
Applicant:

Sanofi, Paris, FR;

Inventors:

Dieter Kadereit, Frankfurt am Main, DE;

Michael Wagner, Frankfurt am Main, DE;

Thomas Olpp, Frankfurt am Main, DE;

Nino Meyer, Frankfurt am Main, DE;

Martin Bossart, Frankfurt am Main, DE;

Andreas Evers, Frankfurt am Main, DE;

Peyman Sakhaii, Frankfurt am Main, DE;

Pradeep K. Dhal, Cambridge, MA (US);

Paul Konowicz, Cambridge, MA (US);

James E. Stefano, Cambridge, MA (US);

Nils Poth, Frankfurt am Main, DE;

Assignee:

SANOFI, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 47/61 (2017.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61K 9/00 (2006.01); A61K 31/728 (2006.01); A61K 38/26 (2006.01); A61K 47/36 (2006.01);
U.S. Cl.
CPC ...
A61K 47/549 (2017.08); A61K 9/0019 (2013.01); A61K 31/728 (2013.01); A61K 38/1703 (2013.01); A61K 38/26 (2013.01); A61K 47/36 (2013.01); A61K 47/61 (2017.08); A61K 47/6903 (2017.08); A61P 3/04 (2018.01); A61P 3/10 (2018.01);
Abstract

The present invention relates to a conjugate or a pharmaceutically acceptable salt thereof comprising an GLP-1/Glucagon receptor agonist, a linker and a hyaluronic acid hydrogel bearing -L1-L2-L-Y—R20 groups, wherein Y represents an GLP-1/Glucagon receptor agonist moiety; and -L is a linker moiety—by formula (Ia),


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