The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2020

Filed:

Dec. 31, 2018
Applicants:

University of Maryland Baltimore County, Baltimore, MD (US);

Allotropic Tech, Llc, Baltimore, MD (US);

Inventors:

Vikram N. Vakharia, Bowie, MD (US);

Robert Balcerzak, Baltimore, MD (US);

Assignees:

UNIVERSITY OF MARYLAND BALTIMORE COUNTY, Baltimore, MD (US);

ALLOTROPIC TECH, LLC, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 9/14 (2006.01); A61P 31/12 (2006.01); A61K 9/113 (2006.01); A61K 39/00 (2006.01); A61K 47/38 (2006.01); A61K 47/44 (2017.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 9/0053 (2013.01); A61K 9/0056 (2013.01); A61K 9/113 (2013.01); A61K 9/14 (2013.01); A61K 9/70 (2013.01); A61K 39/39 (2013.01); A61P 31/12 (2018.01); A61K 47/38 (2013.01); A61K 47/44 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/542 (2013.01); A61K 2039/552 (2013.01);
Abstract

An oral vaccine composition for fish, and related oral vaccine delivery system and methods for making and using such oral vaccine composition and delivery system are described. The oral vaccine composition includes virus-like particles effective to mediate an immunoprotective response in a target fish species, wherein the virus-like particles are contained in biomass of an organism or cell culture in which the virus-like particles have been expressed, optionally further including (i) adjuvant effective to enhance the immunoprotective response of the virus-like particles in the target fish species; (ii) encapsulant protectively associated with the virus-like particles for selective locus bioavailability in the target fish species; and/or (iii) binding agent aggregating the ingredients of the composition with one another.


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