The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2020
Filed:
Apr. 17, 2019
Emory University, Atlanta, GA (US);
The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);
Jing Chen, Atlanta, GA (US);
Jack Arbiser, Atlanta, GA (US);
Brian Pollack, Decatur, GA (US);
Siyuan Xia, Atlanta, GA (US);
Emory University, Atlanta, GA (US);
The United States Government as Represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
This disclosure relates to methods of managing or treating cancer with agents that lower circulating acetoacetate levels, such as hypolipidemic agents, or other agents that antagonize acetoacetate-BRAF V600 mutant binding to attenuate BRAF V600 mutant tumor growth. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of an agent to a subject in need thereof, wherein the agent is dehydroacetic acid, derivative, prodrug, or salt thereof.