The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Feb. 28, 2018
Applicant:

Jw Bioscience, Chungju-si, KR;

Inventors:

Sunghoon Kim, Seoul, KR;

Mi Rim Jin, Seoul, KR;

Young Ha Ahn, Daejeon, KR;

Assignee:

JW BIOSCIENCE, Chungju-si, Chungcheongbuk-Do, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/573 (2006.01); C12Q 1/689 (2018.01); C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); C07K 16/40 (2006.01); C12Q 1/6813 (2018.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07K 16/40 (2013.01); C12Q 1/68 (2013.01); C12Q 1/689 (2013.01); C12Q 1/6813 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/701 (2013.01); C12Y 601/01002 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/9015 (2013.01); G01N 2800/26 (2013.01); G01N 2800/56 (2013.01); Y02A 50/59 (2018.01);
Abstract

The present invention relates to a composition for diagnosing infectious diseases by using a tryptophanyl-tRNA synthase (WRS) and a method for detecting a diagnostic marker and, more specifically, to: a composition for diagnosing infectious diseases, containing a preparation measuring the WRS protein or mRNA expression level; a diagnostic kit; a method for detecting the WRS for providing information required for the diagnosis of infectious diseases, and a method for determining the infectious disease mortality risk by using the WRS. According to the present invention, the WRS is increased only in infection-induced infectious diseases, differentiating non-infectious diseases therefrom, and is rapidly increased in the early stage of infection. In addition, the level of the WRS is closely correlated with the severity and prognosis of diseases or complications induced by infection. Therefore, the WRS can be used as a marker for more rapid and accurate diagnosis, in comparison to a conventional marker for infectious diseases or complications thereof.


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